Treatments for Corona Virus Covid 19

Mar 29, 2020 | 2 comments

What Are The Current Proposed Treatments for Covid 19

Currently, there are some “off label” treatments for the novel coronavirus. Currently, the World Health Organization (WHO) has publically noted some of these drugs many doctors in different countries have used. So what exactly are these drugs and do they have significant side effects or proof of even working?

So what drugs are being tested to combat this serious virus at the moment? Right now hydroxychloroquine, chloroquine, arbidol, remdesivir, and favipiravirme are all in the pipeline to test on patients [1]. Some of the off label use of anti-malaria drugs were touted to work started a small trial in a French hospital. The drug they used there in an attempt to combat Covid-19 was chloroquine or hydroxychloroquine and azithromycin [2]. Even President Trump touted “one of the biggest game-changers in the history of medicine”. However is this combination safe for everyone or is there a chance these drugs could hurt you? The results of the french trial were six patients were asymptomatic, 22 had upper respiratory tract infection symptoms and eight had lower respiratory tract infection symptoms. Twenty cases were treated in this study and showed a significant reduction of the viral carriage at D6-post inclusion compared to controls, and much lower average carrying duration than reported of untreated patients in the literature. Azithromycin added to hydroxychloroquine was significantly more efficient for virus elimination. I want to talk more about the actually harms some of these drugs can cause and what other prescription alternatives, stated above could be a more effective and less damaging form of treatment. 

What Is The Safest Form Of Treatment Currently

So being an advocate of protecting others from harm done by prescription medications I personally have had issues with an antibiotic class of fluoroquinolone. The first and worst option of the proposed treatments, I believe is the drug chloroquine (hydroxychloroquine). The reason I feel this way is the drug is in the class of quinolines. Any antibiotic or antiviral in the quinoline class, I feel all detrimental side effects. So why do I feel this way about this class of drug you may ask? Well, this class of drugs has damaged my nerves, tendons and hormonal system. This statement is not to scare you, however just to inform you of the precautions you could take. Here are some of the drugs below. Please remember all of these drugs have side effects and no serious clinical trial has been performed.

Chloroquine

The first and worst option of the proposed treatments, I believe is the drug chloroquine (hydroxychloroquine). The reason I feel this way is the drug is in the class of quinolines. Any antibiotic or antiviral in the quinoline class, I feel all detrimental side effects. So why do I feel this way about this class of drug you may ask? Well this class of drugs has damaged my nerves, tendons and hormonal system. This statement is not to scare you, however just to inform you of the precautions you could take. Here are some of the drugs below.

headache,loss of appetite, diarrhea, upset stomach, stomach pain, skin rash or itching, hair loss, mood or mental changes, seeing light flashes and streaks, blurred vision, difficulty hearing, ringing in ears, muscle weakness, drowsiness, vomiting, irregular heartbeats, convulsions, difficulty breathing [4] In a panic to treat this and a really soft study in France has lead leading doctors to sound the alarm on this class of drugs.

“Hydroxychloroquine and chloroquine can cause severe cardiac toxicity, and in high doses over a long duration, can cause retinal damage and lead to permanent blindness,” said Dr. Alvin Bronstein, DOH Emergency Medical Services and Injury Prevention System Branch Chief.

“Individuals using these medications without physician supervision run serious risks of side effects and potential overdoses. Other medications are being touted, but nothing has been proven to be effective and may even do more harm than good,” Bronstein added.

I REST MY CASE….. See here for my proactive steps to get my immune system built for this.

 

The Other Medications For Coronavirus

Remdesivir

A Gilead Sciences drug that was originally tested in people with Ebola, remdesivir, is being repurposed to see if it can effectively treat COVID-19. The drug was found not to be effective in Ebola, but in lab studies, it has proven effective at inhibiting the growth of similar viruses, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). In a petri dish, remdesivir can prevent human cells from becoming infected with SARS-CoV-2. But what does that mean for the current epidemic and is the drug worth taking? The Food and Drug Administration has approved the use of remdesivir for severe cases of Covid-19. The good news is there is trials in multiple countries. Five clinical trials in China and the U.S. are currently evaluating whether remdesevir can reduce complications or shorten the disease course in COVID-19 patients.

“There’s only one drug right now that we think may have real efficacy,” Bruce Aylward of the World Health Organization said last month, as reported by STAT. “And that’s remdesivir.”

The FDA has not cleared the drug for use on all cases of the virus and lab tests are still being reviewed. Also are the benefits worth the side effects? So right now there are proven side effects such as liver enzyme increase, nausea, vomiting. I feel this drug to be a much safer alternative to the drug class of quinolines. 

Favipiravir

There is also this Japanese anti-flu drug favipiravir (brand name Avigan) being effective against SARS-CoV-2. This is the virus that causes COVID-19. There is little to no tests in the United States of this drug working. However, Japan,South Korea and China have used this drug to treat the coronavirus. 

So far, reports suggest the drug has been tested in 340 individuals in Wuhan and Shenzhen. “It has a high degree of safety and is clearly effective in treatment,” Zhang Xinmin, of China’s science and technology ministry, said March 17, The Guardian reported. If your looking for the side effects see here

Arbidol

Arbidol or Umifenovir, is a broad-spectrum antiviral only available in China and Russia and was previously used against certain influenza outbreaks in the past. Based on earlier vitro studies and clinical assessments, the researchers conducted two cohort studies involving 27 families and 124 healthcare workers who had high risk of exposure to the Covid-19 disease, using Arbidol, Oseltamivir and placebo for the different sub-groups for each of the cohorts. After a period of 24 days and using standard nucleic acid diagnostic platforms, it was found that those that used Arbidol reported an extremely low number of cases contracting the Covid-19 disease whereas those using Oseltamivir had no effect in preventing transmissions. There is little evidence here in the United States about this treatment, but I wanted to let you know it is here. For more information on the drug see here

 

In Closing And My Thoughts

With all the sources of media and the constant scare of getting this can create panic and hysteria. How often we easily forget the Swine Flu H1N1 that caused more disease and mortality than COVID-19. How easily we forget that the annual statistics for the “regular” Influenza dwarf the stats for COVID-19.How easily we forget that the death rates from automobile accidents and obesity easily trounce the death rates from COVID-19. For now, social distancing can help but its asymptomatic people that are spreading the virus which is inevitable.  We cannot live in fear under the notion that the apocalypse is upon us and that we must run away in order to protect ourselves. This idea does not have merit and is supported by the media’s recency bias about how dangerous this virus is. For now I implore you to keep your hands clean and wash for at least the time it takes you to sing happy birthday and boost your immune system with my article here

References

Dong L, e., 2020. Discovering Drugs To Treat Coronavirus Disease 2019 (COVID-19). – Pubmed – NCBI. [online] Ncbi.nlm.nih.gov. Available at: <https://www.ncbi.nlm.nih.gov/pubmed/32147628> [Accessed 29 March 2020].

Gautret P, e., 2020. Hydroxychloroquine And Azithromycin As A Treatment Of COVID-19: Results Of An Open-Label Non-Randomized Clinical Trial. – Pubmed – NCBI. [online] Ncbi.nlm.nih.gov. Available at: <https://www.ncbi.nlm.nih.gov/pubmed/32205204> [Accessed 29 March 2020].

Medlineplus.gov. 2020. Chloroquine: Medlineplus Drug Information. [online] Available at: <https://medlineplus.gov/druginfo/meds/a682318.html> [Accessed 29 March 2020].

Medlineplus.gov. 2020. Chloroquine: Medlineplus Drug Information. [online] Available at: <https://medlineplus.gov/druginfo/meds/a682318.html> [Accessed 29 March 2020].

Medlineplus.gov. 2020. Chloroquine: Medlineplus Drug Information. [online] Available at: <https://medlineplus.gov/druginfo/meds/a682318.html> [Accessed 29 March 2020].

 

Jason Sousa

Jason Sousa

Healthopsy Coach

My health changed when I took healing into my own hands. Using what I have learned with diet, lifesyle changes and knowledge. I hope this site helps you on your journey.

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2 Comments

  1. jesse fredette

    jason i take 200mgs a day hydrouclorine probbly misspelled a day for my RA

    Reply
    • healthopsy

      There is safer alternatives like nebulize hydrogen peroxide and glutathione. Also remdesivir seems to have a safer profile.

      Reply

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